MRI-Based Computational Model of Heterogeneous Tracer Transport following Local Infusion into a Mouse Hind Limb Tumor

Systemic drug delivery to solid tumors involving macromolecular therapeutic agents is challenging for many reasons. Amongst them is their chaotic microvasculature which often leads to inadequate and uneven uptake of the drug. Localized drug delivery can circumvent such obstacles and convection-enhan...

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Detalles Bibliográficos
Autores principales: Magdoom, Kulam Najmudeen, Pishko, Gregory L., Rice, Lori, Pampo, Chris, Siemann, Dietmar W., Sarntinoranont, Malisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949671/
https://www.ncbi.nlm.nih.gov/pubmed/24619021
http://dx.doi.org/10.1371/journal.pone.0089594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949671/
https://www.ncbi.nlm.nih.gov/pubmed/24619021
http://dx.doi.org/10.1371/journal.pone.0089594

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