Gene Expression Profiling in Tibial Muscular Dystrophy Reveals Unfolded Protein Response and Altered Autophagy

Tibial muscular dystrophy (TMD) is a late onset, autosomal dominant distal myopathy that results from mutations in the two last domains of titin. The cascade of molecular events leading from the causative Titin mutations to the preterm death of muscle cells in TMD is largely unknown. In this study w...

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Detalles Bibliográficos
Autores principales: Screen, Mark, Raheem, Olayinka, Holmlund-Hampf, Jeanette, Jonson, Per Harald, Huovinen, Sanna, Hackman, Peter, Udd, Bjarne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949689/
https://www.ncbi.nlm.nih.gov/pubmed/24618559
http://dx.doi.org/10.1371/journal.pone.0090819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949689/
https://www.ncbi.nlm.nih.gov/pubmed/24618559
http://dx.doi.org/10.1371/journal.pone.0090819

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