Whole Genome Sequencing of Mycobacterium tuberculosis Reveals Slow Growth and Low Mutation Rates during Latent Infections in Humans

Very little is known about the growth and mutation rates of Mycobacterium tuberculosis during latent infection in humans. However, studies in rhesus macaques have suggested that latent infections have mutation rates that are higher than that observed during active tuberculosis disease. Elevated muta...

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Detalles Bibliográficos
Autores principales: Colangeli, Roberto, Arcus, Vic L., Cursons, Ray T., Ruthe, Ali, Karalus, Noel, Coley, Kathy, Manning, Shannon D., Kim, Soyeon, Marchiano, Emily, Alland, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949705/
https://www.ncbi.nlm.nih.gov/pubmed/24618815
http://dx.doi.org/10.1371/journal.pone.0091024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949705/
https://www.ncbi.nlm.nih.gov/pubmed/24618815
http://dx.doi.org/10.1371/journal.pone.0091024

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