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Whole Genome Sequencing of Mycobacterium tuberculosis Reveals Slow Growth and Low Mutation Rates during Latent Infections in Humans
Very little is known about the growth and mutation rates of Mycobacterium tuberculosis during latent infection in humans. However, studies in rhesus macaques have suggested that latent infections have mutation rates that are higher than that observed during active tuberculosis disease. Elevated muta...
Autores principales: | Colangeli, Roberto, Arcus, Vic L., Cursons, Ray T., Ruthe, Ali, Karalus, Noel, Coley, Kathy, Manning, Shannon D., Kim, Soyeon, Marchiano, Emily, Alland, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949705/ https://www.ncbi.nlm.nih.gov/pubmed/24618815 http://dx.doi.org/10.1371/journal.pone.0091024 |
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