A Generic Method for Design of Oligomer-Specific Antibodies

Antibodies that preferentially and specifically target pathological oligomeric protein and peptide assemblies, as opposed to their monomeric and amyloid counterparts, provide therapeutic and diagnostic opportunities for protein misfolding diseases. Unfortunately, the molecular properties associated...

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Detalles Bibliográficos
Autores principales: Brännström, Kristoffer, Lindhagen-Persson, Malin, Gharibyan, Anna L., Iakovleva, Irina, Vestling, Monika, Sellin, Mikael E., Brännström, Thomas, Morozova-Roche, Ludmilla, Forsgren, Lars, Olofsson, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949727/
https://www.ncbi.nlm.nih.gov/pubmed/24618582
http://dx.doi.org/10.1371/journal.pone.0090857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949727/
https://www.ncbi.nlm.nih.gov/pubmed/24618582
http://dx.doi.org/10.1371/journal.pone.0090857

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