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The predictive role of pretreatment epidermal growth factor receptor T790M mutation on the progression-free survival of tyrosine-kinase inhibitor-treated non-small cell lung cancer patients: a meta-analysis

PURPOSE: Subclones bearing the epidermal growth factor receptor (EGFR) T790M mutation concomitant with deletional mutation in exon 19 (Del19) or a point mutation in exon 21 (L858R) have been reported in non-small cell lung cancer patients before any EGFR tyrosine-kinase inhibitor (TKI) treatment. Th...

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Detalles Bibliográficos
Autores principales: Ding, Ding, Yu, Yongfeng, Li, Ziming, Niu, Xiaomin, Lu, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949752/
https://www.ncbi.nlm.nih.gov/pubmed/24623981
http://dx.doi.org/10.2147/OTT.S58870