Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer

The fusion of echinoderm microtubule-associated protein-like 4 with anaplastic lymphoma kinase (ALK) was identified as a transforming gene for lung cancer in 2007. This genetic rearrangement accounts for 2%–5% of non-small-cell lung cancer (NSCLC) cases, occurring predominantly in younger individual...

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Detalles Bibliográficos
Autores principales: Iwama, Eiji, Okamoto, Isamu, Harada, Taishi, Takayama, Koichi, Nakanishi, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949762/
https://www.ncbi.nlm.nih.gov/pubmed/24623980
http://dx.doi.org/10.2147/OTT.S38868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949762/
https://www.ncbi.nlm.nih.gov/pubmed/24623980
http://dx.doi.org/10.2147/OTT.S38868

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