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Genetic Deletion of Prostacyclin IP Receptor Exacerbates Transient Global Cerebral Ischemia in Aging Mice

Transient global cerebral ischemia causes delayed neuronal death in the hippocampal CA1 region. It also induces an up regulation of cyclooxygenase 2 (COX-2), which generates several metabolites of arachidonic acid, known as prostanoids, including Prostaglandin I(2) (PGI(2)). The present study invest...

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Detalles Bibliográficos
Autores principales: Shakil, Hania, Saleem, Sofiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950203/
https://www.ncbi.nlm.nih.gov/pubmed/24634780
http://dx.doi.org/10.3390/brainsci3031095