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LFG-500 Inhibits the Invasion of Cancer Cells via Down-Regulation of PI3K/AKT/NF-κB Signaling Pathway

Cancer cell invasion, one of the crucial events in local growth and metastatic spread of tumors, possess a broad spectrum of mechanisms, especially altered expression of matrix metalloproteinases. LFG-500 is a novel synthesized flavonoid with strong anti-cancer activity, whose exact molecular mechan...

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Detalles Bibliográficos
Autores principales: Li, Chenglin, Li, Fanni, Zhao, Kai, Yao, Jing, Cheng, Yao, Zhao, Li, Li, Zhiyu, Lu, Na, Guo, Qinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950212/
https://www.ncbi.nlm.nih.gov/pubmed/24618693
http://dx.doi.org/10.1371/journal.pone.0091332