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Altered Expression of PTEN and Its Major Regulator MicroRNA-21 in Pulmonary Neuroendocrine Tumors

BACKGROUND: Phosphatase and tensin homolog on chromosome ten (PTEN) is one of the most frequently inactivated tumor suppressors in various tumor types. MicroRNA-21 (miR-21) may affect tumor progression by post-transcriptional repression of expression of tumor suppressors, such as PTEN. This study wa...

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Detalles Bibliográficos
Autores principales: Lee, Hyoun Wook, Ha, Seung Yeon, Roh, Mee Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and The Korean Society for Cytopathology 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950230/
https://www.ncbi.nlm.nih.gov/pubmed/24627690
http://dx.doi.org/10.4132/KoreanJPathol.2014.48.1.17