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Bacterial Delivery of TALEN Proteins for Human Genome Editing

Transcription Activator-Like Effector Nucleases (TALENs) are a novel class of sequence-specific nucleases that have recently gained prominence for its ease of production and high efficiency in genome editing. A TALEN pair recognizes specific DNA sequences and introduce double-strand break in the tar...

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Detalles Bibliográficos
Autores principales: Jia, Jingyue, Jin, Yongxin, Bian, Ting, Wu, Donghai, Yang, Lijun, Terada, Naohiro, Wu, Weihui, Jin, Shouguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950253/
https://www.ncbi.nlm.nih.gov/pubmed/24618838
http://dx.doi.org/10.1371/journal.pone.0091547