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Drug Similarity Search Based on Combined Signatures in Gene Expression Profiles

OBJECTIVES: Recently, comparison of drug responses on gene expression has been a major approach to identifying the functional similarity of drugs. Previous studies have mostly focused on a single feature, the expression differences of individual genes. We provide a more robust and accurate method to...

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Detalles Bibliográficos
Autores principales: Cha, Kihoon, Kim, Min-Sung, Oh, Kimin, Shin, Hyunjung, Yi, Gwan-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Medical Informatics 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950266/
https://www.ncbi.nlm.nih.gov/pubmed/24627819
http://dx.doi.org/10.4258/hir.2014.20.1.52