Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

Antibiotics can have significant and long lasting effects on the gastrointestinal tract microbiota, reducing colonization resistance against pathogens including Clostridium difficile. Here we show that antibiotic treatment induces substantial changes in the gut microbial community and in the metabol...

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Detalles Bibliográficos
Autores principales: Theriot, Casey M., Koenigsknecht, Mark J., Carlson, Paul E., Hatton, Gabrielle E., Nelson, Adam M., Li, Bo, Huffnagle, Gary B., Li, Jun, Young, Vincent B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950275/
https://www.ncbi.nlm.nih.gov/pubmed/24445449
http://dx.doi.org/10.1038/ncomms4114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950275/
https://www.ncbi.nlm.nih.gov/pubmed/24445449
http://dx.doi.org/10.1038/ncomms4114

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