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Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection
Antibiotics can have significant and long lasting effects on the gastrointestinal tract microbiota, reducing colonization resistance against pathogens including Clostridium difficile. Here we show that antibiotic treatment induces substantial changes in the gut microbial community and in the metabol...
Autores principales: | Theriot, Casey M., Koenigsknecht, Mark J., Carlson, Paul E., Hatton, Gabrielle E., Nelson, Adam M., Li, Bo, Huffnagle, Gary B., Li, Jun, Young, Vincent B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950275/ https://www.ncbi.nlm.nih.gov/pubmed/24445449 http://dx.doi.org/10.1038/ncomms4114 |
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