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The Cellular Distribution and Ser262 Phosphorylation of Tau Protein Are Regulated by BDNF In Vitro

The brain-enriched microtubule-associated protein tau, a critical regulator of cytoskeletal dynamics, forms insoluble aggregates in a number of neurodegenerative diseases termed tauopathies, including Alzheimer's disease (AD). Hyperphosphorylation of tau protein is an important mechanism for ag...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Zhou, Zhou, Zhang, Lei, Xu, Shangcheng, Chen, Chunhai, Yu, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950283/
https://www.ncbi.nlm.nih.gov/pubmed/24618580
http://dx.doi.org/10.1371/journal.pone.0091793