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Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo

Increased expression of HBEGF in ER negative breast tumors is correlated with enhanced metastasis to distant organ sites and more rapid disease recurrence upon removal of the primary tumor. Our previous work has demonstrated a paracrine loop between breast cancer cells and macrophages in which the t...

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Detalles Bibliográficos
Autores principales: Zhou, Zhen Ni, Sharma, Ved P., Beaty, Brian T., Roh-Johnson, Minna, Peterson, Esther A., Van Rooijen, Nico, Kenny, Paraic A., Wiley, H. Steven, Condeelis, John S., Segall, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950352/
https://www.ncbi.nlm.nih.gov/pubmed/24013225
http://dx.doi.org/10.1038/onc.2013.363