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Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo
Increased expression of HBEGF in ER negative breast tumors is correlated with enhanced metastasis to distant organ sites and more rapid disease recurrence upon removal of the primary tumor. Our previous work has demonstrated a paracrine loop between breast cancer cells and macrophages in which the t...
Autores principales: | Zhou, Zhen Ni, Sharma, Ved P., Beaty, Brian T., Roh-Johnson, Minna, Peterson, Esther A., Van Rooijen, Nico, Kenny, Paraic A., Wiley, H. Steven, Condeelis, John S., Segall, Jeffrey E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950352/ https://www.ncbi.nlm.nih.gov/pubmed/24013225 http://dx.doi.org/10.1038/onc.2013.363 |
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