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Comprehensive Functional Analysis of N-Linked Glycans on Ebola Virus GP1

Ebola virus (EBOV) entry requires the virion surface-associated glycoprotein (GP) that is composed of a trimer of heterodimers (GP1/GP2). The GP1 subunit contains two heavily glycosylated domains, the glycan cap and the mucin-like domain (MLD). The glycan cap contains only N-linked glycans, whereas...

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Detalles Bibliográficos
Autores principales: Lennemann, Nicholas J., Rhein, Bethany A., Ndungo, Esther, Chandran, Kartik, Qiu, Xiangguo, Maury, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950510/
https://www.ncbi.nlm.nih.gov/pubmed/24473128
http://dx.doi.org/10.1128/mBio.00862-13