Protein comparability assessments and potential applicability of high throughput biophysical methods and data visualization tools to compare physical stability profiles

In this review, some of the challenges and opportunities encountered during protein comparability assessments are summarized with an emphasis on developing new analytical approaches to better monitor higher-order protein structures. Several case studies are presented using high throughput biophysica...

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Detalles Bibliográficos
Autores principales: Alsenaidy, Mohammad A., Jain, Nishant K., Kim, Jae H., Middaugh, C. Russell, Volkin, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950620/
https://www.ncbi.nlm.nih.gov/pubmed/24659968
http://dx.doi.org/10.3389/fphar.2014.00039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950620/
https://www.ncbi.nlm.nih.gov/pubmed/24659968
http://dx.doi.org/10.3389/fphar.2014.00039

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