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Protein comparability assessments and potential applicability of high throughput biophysical methods and data visualization tools to compare physical stability profiles
In this review, some of the challenges and opportunities encountered during protein comparability assessments are summarized with an emphasis on developing new analytical approaches to better monitor higher-order protein structures. Several case studies are presented using high throughput biophysica...
Autores principales: | Alsenaidy, Mohammad A., Jain, Nishant K., Kim, Jae H., Middaugh, C. Russell, Volkin, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950620/ https://www.ncbi.nlm.nih.gov/pubmed/24659968 http://dx.doi.org/10.3389/fphar.2014.00039 |
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