FeON-FeOFF: the Helicobacter pylori Fur regulator commutates iron-responsive transcription by discriminative readout of opposed DNA grooves

Most transcriptional regulators bind nucleotide motifs in the major groove, although some are able to recognize molecular determinants conferred by the minor groove of DNA. Here we report a transcriptional commutator switch that exploits the alternative readout of grooves to mediate opposite output...

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Detalles Bibliográficos
Autores principales: Agriesti, Francesca, Roncarati, Davide, Musiani, Francesco, Del Campo, Cristian, Iurlaro, Mario, Sparla, Francesca, Ciurli, Stefano, Danielli, Alberto, Scarlato, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950669/
https://www.ncbi.nlm.nih.gov/pubmed/24322295
http://dx.doi.org/10.1093/nar/gkt1258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950669/
https://www.ncbi.nlm.nih.gov/pubmed/24322295
http://dx.doi.org/10.1093/nar/gkt1258

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