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PGC7 suppresses TET3 for protecting DNA methylation

Ten-eleven translocation (TET) family enzymes convert 5-methylcytosine to 5-hydroxylmethylcytosine. However, the molecular mechanism that regulates this biological process is not clear. Here, we show the evidence that PGC7 (also known as Dppa3 or Stella) interacts with TET2 and TET3 both in vitro an...

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Detalles Bibliográficos
Autores principales: Bian, Chunjing, Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950671/
https://www.ncbi.nlm.nih.gov/pubmed/24322296
http://dx.doi.org/10.1093/nar/gkt1261