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Causal inference of gene regulation with subnetwork assembly from genetical genomics data

Deciphering the causal networks of gene interactions is critical for identifying disease pathways and disease-causing genes. We introduce a method to reconstruct causal networks based on exploring phenotype-specific modules in the human interactome and including the expression quantitative trait loc...

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Detalles Bibliográficos
Autores principales: Peng, Chien-Hua, Jiang, Yi-Zhi, Tai, An-Shun, Liu, Chun-Bin, Peng, Shih-Chi, Liao, Chun-Ta, Yen, Tzu-Chen, Hsieh, Wen-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950678/
https://www.ncbi.nlm.nih.gov/pubmed/24322297
http://dx.doi.org/10.1093/nar/gkt1277