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Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ

The YaeJ protein is a codon-independent release factor with peptidyl-tRNA hydrolysis (PTH) activity, and functions as a stalled-ribosome rescue factor in Escherichia coli. To identify residues required for YaeJ function, we performed mutational analysis for in vitro PTH activity towards rescue of ri...

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Detalles Bibliográficos
Autores principales: Kogure, Hiroyuki, Handa, Yoshihiro, Nagata, Masahiro, Kanai, Naoto, Güntert, Peter, Kubota, Kenji, Nameki, Nobukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950681/
https://www.ncbi.nlm.nih.gov/pubmed/24322300
http://dx.doi.org/10.1093/nar/gkt1280