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DICE, an efficient system for iterative genomic editing in human pluripotent stem cells
To reveal the full potential of human pluripotent stem cells, new methods for rapid, site-specific genomic engineering are needed. Here, we describe a system for precise genetic modification of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). We identified a novel human...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950688/ https://www.ncbi.nlm.nih.gov/pubmed/24304893 http://dx.doi.org/10.1093/nar/gkt1290 |