DICE, an efficient system for iterative genomic editing in human pluripotent stem cells

To reveal the full potential of human pluripotent stem cells, new methods for rapid, site-specific genomic engineering are needed. Here, we describe a system for precise genetic modification of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). We identified a novel human...

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Detalles Bibliográficos
Autores principales: Zhu, Fangfang, Gamboa, Matthew, Farruggio, Alfonso P., Hippenmeyer, Simon, Tasic, Bosiljka, Schüle, Birgitt, Chen-Tsai, Yanru, Calos, Michele P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950688/
https://www.ncbi.nlm.nih.gov/pubmed/24304893
http://dx.doi.org/10.1093/nar/gkt1290

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