Transient kinetics measured with force steps discriminate between double-stranded DNA elongation and melting and define the reaction energetics

Under a tension of ∼65 pN, double-stranded DNA undergoes an overstretching transition from its basic (B-form) conformation to a 1.7 times longer conformation whose nature is only recently starting to be understood. Here we provide a structural and thermodynamic characterization of the transition by...

Descripción completa

Detalles Bibliográficos
Autores principales: Bongini, Lorenzo, Melli, Luca, Lombardi, Vincenzo, Bianco, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950695/
https://www.ncbi.nlm.nih.gov/pubmed/24353317
http://dx.doi.org/10.1093/nar/gkt1297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950695/
https://www.ncbi.nlm.nih.gov/pubmed/24353317
http://dx.doi.org/10.1093/nar/gkt1297

Ejemplares similares