Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase

All positive-stranded RNA viruses with genomes >∼7 kb encode helicases, which generally are poorly characterized. The core of the nidovirus superfamily 1 helicase (HEL1) is associated with a unique N-terminal zinc-binding domain (ZBD) that was previously implicated in helicase regulation, genome...

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Detalles Bibliográficos
Autores principales: Deng, Zengqin, Lehmann, Kathleen C., Li, Xiaorong, Feng, Chong, Wang, Guoqiang, Zhang, Qi, Qi, Xiaoxuan, Yu, Lin, Zhang, Xingliang, Feng, Wenhai, Wu, Wei, Gong, Peng, Tao, Ye, Posthuma, Clara C., Snijder, Eric J., Gorbalenya, Alexander E., Chen, Zhongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950703/
https://www.ncbi.nlm.nih.gov/pubmed/24369429
http://dx.doi.org/10.1093/nar/gkt1310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950703/
https://www.ncbi.nlm.nih.gov/pubmed/24369429
http://dx.doi.org/10.1093/nar/gkt1310

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