SUMOylation of the polycomb group protein L3MBTL2 facilitates repression of its target genes

Lethal(3) malignant brain tumour like 2 (L3MBTL2) is an integral component of the polycomb repressive complex 1.6 (PRC1.6) and has been implicated in transcriptional repression and chromatin compaction. Here, we show that L3MBTL2 is modified by SUMO2/3 at lysine residues 675 and 700 close to the C-t...

Descripción completa

Detalles Bibliográficos
Autores principales: Stielow, Christina, Stielow, Bastian, Finkernagel, Florian, Scharfe, Maren, Jarek, Michael, Suske, Guntram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950706/
https://www.ncbi.nlm.nih.gov/pubmed/24369422
http://dx.doi.org/10.1093/nar/gkt1317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950706/
https://www.ncbi.nlm.nih.gov/pubmed/24369422
http://dx.doi.org/10.1093/nar/gkt1317

Ejemplares similares