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SUMOylation of the polycomb group protein L3MBTL2 facilitates repression of its target genes
Lethal(3) malignant brain tumour like 2 (L3MBTL2) is an integral component of the polycomb repressive complex 1.6 (PRC1.6) and has been implicated in transcriptional repression and chromatin compaction. Here, we show that L3MBTL2 is modified by SUMO2/3 at lysine residues 675 and 700 close to the C-t...
Autores principales: | Stielow, Christina, Stielow, Bastian, Finkernagel, Florian, Scharfe, Maren, Jarek, Michael, Suske, Guntram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950706/ https://www.ncbi.nlm.nih.gov/pubmed/24369422 http://dx.doi.org/10.1093/nar/gkt1317 |
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