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c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs

CpG methylation in mammalian DNA is known to interfere with gene expression by inhibiting the binding of transactivators to their cognate sequence motifs or recruiting proteins involved in gene repression. An Epstein–Barr virus-encoded transcription factor, Zta, was the first example of a sequence-s...

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Detalles Bibliográficos
Autores principales: Gustems, Montse, Woellmer, Anne, Rothbauer, Ulrich, Eck, Sebastian H., Wieland, Thomas, Lutter, Dominik, Hammerschmidt, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950711/
https://www.ncbi.nlm.nih.gov/pubmed/24371273
http://dx.doi.org/10.1093/nar/gkt1323