The contribution of pseudouridine to stabilities and structure of RNAs

Thermodynamic data are reported revealing that pseudouridine (Ψ) can stabilize RNA duplexes when replacing U and forming Ψ-A, Ψ-G, Ψ-U and Ψ-C pairs. Stabilization is dependent on type of base pair, position of Ψ within the RNA duplex, and type and orientation of adjacent Watson–Crick pairs. NMR spe...

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Detalles Bibliográficos
Autores principales: Kierzek, Elzbieta, Malgowska, Magdalena, Lisowiec, Jolanta, Turner, Douglas H., Gdaniec, Zofia, Kierzek, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950712/
https://www.ncbi.nlm.nih.gov/pubmed/24369424
http://dx.doi.org/10.1093/nar/gkt1330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950712/
https://www.ncbi.nlm.nih.gov/pubmed/24369424
http://dx.doi.org/10.1093/nar/gkt1330

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