Cargando…

Tracking the processing of damaged DNA double-strand break ends by ligation-mediated PCR: increased persistence of 3′-phosphoglycolate termini in SCAN1 cells

To track the processing of damaged DNA double-strand break (DSB) ends in vivo, a method was devised for quantitative measurement of 3′-phosphoglycolate (PG) termini on DSBs induced by the non-protein chromophore of neocarzinostatin (NCS-C) in the human Alu repeat. Following exposure of cells to NCS-...

Descripción completa

Detalles Bibliográficos
Autores principales: Akopiants, Konstantin, Mohapatra, Susovan, Menon, Vijay, Zhou, Tong, Valerie, Kristoffer, Povirk, Lawrence F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950721/
https://www.ncbi.nlm.nih.gov/pubmed/24371269
http://dx.doi.org/10.1093/nar/gkt1347