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Tracking the processing of damaged DNA double-strand break ends by ligation-mediated PCR: increased persistence of 3′-phosphoglycolate termini in SCAN1 cells

To track the processing of damaged DNA double-strand break (DSB) ends in vivo, a method was devised for quantitative measurement of 3′-phosphoglycolate (PG) termini on DSBs induced by the non-protein chromophore of neocarzinostatin (NCS-C) in the human Alu repeat. Following exposure of cells to NCS-...

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Detalles Bibliográficos
Autores principales:	Akopiants, Konstantin, Mohapatra, Susovan, Menon, Vijay, Zhou, Tong, Valerie, Kristoffer, Povirk, Lawrence F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950721/ https://www.ncbi.nlm.nih.gov/pubmed/24371269 http://dx.doi.org/10.1093/nar/gkt1347

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