Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes

Understanding the structure of interphase chromosomes is essential to elucidate regulatory mechanisms of gene expression. During recent years, high-throughput DNA sequencing expanded the power of chromosome conformation capture (3C) methods that provide information about reciprocal spatial proximity...

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Detalles Bibliográficos
Autores principales: Benedetti, Fabrizio, Dorier, Julien, Burnier, Yannis, Stasiak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950722/
https://www.ncbi.nlm.nih.gov/pubmed/24366878
http://dx.doi.org/10.1093/nar/gkt1353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950722/
https://www.ncbi.nlm.nih.gov/pubmed/24366878
http://dx.doi.org/10.1093/nar/gkt1353

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