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Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes
Understanding the structure of interphase chromosomes is essential to elucidate regulatory mechanisms of gene expression. During recent years, high-throughput DNA sequencing expanded the power of chromosome conformation capture (3C) methods that provide information about reciprocal spatial proximity...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950722/ https://www.ncbi.nlm.nih.gov/pubmed/24366878 http://dx.doi.org/10.1093/nar/gkt1353 |