Evaluation of multiplex ligation-dependent probe amplification analysis versus multiplex polymerase chain reaction assays in the detection of dystrophin gene rearrangements in an Iranian population subset

BACKGROUND: The Duchenne muscular dystrophy (DMD) gene is located in the short arm of the X chromosome (Xp21). It spans 2.4 Mb of the human genomic DNA and is composed of 79 exons. Mutations in the Dystrophin gene result in DMD and Becker muscular dystrophy. In this study, the efficiency of multiple...

Descripción completa

Detalles Bibliográficos
Autores principales: Nouri, Nayereh, Fazel-Najafabadi, Esmat, Salehi, Mansoor, Hosseinzadeh, Majid, Behnam, Mahdieh, Ghazavi, Mohammad Reza, Sedghi, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950794/
https://www.ncbi.nlm.nih.gov/pubmed/24627880
http://dx.doi.org/10.4103/2277-9175.125862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950794/
https://www.ncbi.nlm.nih.gov/pubmed/24627880
http://dx.doi.org/10.4103/2277-9175.125862

Ejemplares similares