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G-CSF and G-CSFR are highly expressed in human gastric and colon cancers and promote carcinoma cell proliferation and migration

BACKGROUND: Granulocyte colony-stimulating factor (G-CSF) is a pro-inflammatory cytokine that stimulates myeloid stem cell maturation, proliferation, and migration into circulation. Despite being a known growth factor, the impact of G-CSF on solid tumours has not been well examined. G-CSF receptor (...

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Detalles Bibliográficos
Autores principales: Morris, K T, Khan, H, Ahmad, A, Weston, L L, Nofchissey, R A, Pinchuk, I V, Beswick, E J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950854/
https://www.ncbi.nlm.nih.gov/pubmed/24448357
http://dx.doi.org/10.1038/bjc.2013.822