Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer

BACKGROUND: CXC chemokine receptor 4 (CXCR4) and its ligand stromal cell-derived factor-1α (SDF-1α, also known as CXCL12) have important roles in promoting tumour growth and metastasis. Therefore, targeting CXCR4 could be a promising strategy for treatment of human cancer. METHODS: To achieve this g...

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Detalles Bibliográficos
Autores principales: Yang, Q, Zhang, F, Ding, Y, Huang, J, Chen, S, Wu, Q, Wang, Z, Chen, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950870/
https://www.ncbi.nlm.nih.gov/pubmed/24448360
http://dx.doi.org/10.1038/bjc.2014.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950870/
https://www.ncbi.nlm.nih.gov/pubmed/24448360
http://dx.doi.org/10.1038/bjc.2014.1

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