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De Novo Design of Ln(III) Coiled Coils for Imaging Applications

[Image: see text] A new peptide sequence (MB1) has been designed which, in the presence of a trivalent lanthanide ion, has been programmed to self-assemble to form a three stranded metallo-coiled coil, Ln(III)(MB1)(3). The binding site has been incorporated into the hydrophobic core using natural am...

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Detalles Bibliográficos
Autores principales: Berwick, Matthew R., Lewis, David J., Jones, Andrew W., Parslow, Rosemary A., Dafforn, Timothy R., Cooper, Helen J., Wilkie, John, Pikramenou, Zoe, Britton, Melanie M., Peacock, Anna F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950886/
https://www.ncbi.nlm.nih.gov/pubmed/24405157
http://dx.doi.org/10.1021/ja408741h