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Simvastatin attenuates radiation-induced tissue damage in mice

The aim of this study was to investigate the protective effect of simvastatin against radiation-induced tissue injury in mice. Mice were radiated with 4 Gy or 8 Gy after 20 mg/kg/d simvastatin treatment over 2 weeks. Morphological changes were observed in the jejunum and bone marrow, and apoptotic c...

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Detalles Bibliográficos
Autores principales: Zhao, Xinbin, Yang, Hong, Jiang, Guojun, Ni, Min, Deng, Yaping, Cai, Jian, Li, Zhangpeng, Shen, Fuming, Tao, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951077/
https://www.ncbi.nlm.nih.gov/pubmed/24105712
http://dx.doi.org/10.1093/jrr/rrt115