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Rosamines Targeting the Cancer Oxidative Phosphorylation Pathway

Reprogramming of energy metabolism is pivotal to cancer, so mitochondria are potential targets for anticancer therapy. A prior study has demonstrated the anti-proliferative activity of a new class of mitochondria-targeting rosamines. This present study describes in vitro cytotoxicity of second-gener...

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Detalles Bibliográficos
Autores principales: Lim, Siang Hui, Wu, Liangxing, Kiew, Lik Voon, Chung, Lip Yong, Burgess, Kevin, Lee, Hong Boon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951181/
https://www.ncbi.nlm.nih.gov/pubmed/24622277
http://dx.doi.org/10.1371/journal.pone.0082934