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Development and Validation of a Gas Chromatography Method for the Trace Level Determination of Allylamine in Sevelamer Hydrochloride and Sevelamer Carbonate Drug Substances

A capillary gas chromatography method using a flame ionization detector has been developed for the trace analysis of allylamine (AA) in sevelamer hydrochloride (SVH) and sevelamer carbonate (SVC) drug substances. The method utilized a mega bore capillary column DB-CAM (30 m × 0.53 mm × 1.0 μm) with...

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Detalles Bibliográficos
Autores principales: Kadiyala, Raju V. S. N., Kothapalli, Pavan Kumar S. R., Peddolla, Madhava Reddy, Rajput, Pradeep, Sharma, Hemant Kumar, Budeti, Shankar Reddy, Gandham, Himabindu, Nowduri, Annapurna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951223/
https://www.ncbi.nlm.nih.gov/pubmed/24634846
http://dx.doi.org/10.3797/scipharm.1309-12