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Isolation and Evaluation of the Enantiospecific Antitubercular Activity of a Novel Triazole Compound

Cyclohex-3-enyl(5-phenyl-4H-1,2,4-triazol-3-yl)methanol (MSDRT 12) is a novel triazole-based antitubercular compound with two chiral centers. To evaluate the enantiospecific antitubercular activity, the four stereoisomers were isolated using preparative chiral chromatography and the individual stere...

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Detalles Bibliográficos
Autores principales: Shekar, Radha, Sinha, Barij Nayan, Mukhopadhya, Arindam, Degani, Mariam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951235/
https://www.ncbi.nlm.nih.gov/pubmed/24634844
http://dx.doi.org/10.3797/scipharm.1308-15