Cargando…

Nonvesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

Phosphorylated sphingolipids [ceramide-1-phosphate (C1P) and sphingosine-1-phosphate (S1P)] have emerged as key regulators of cell growth, survival, migration, and inflammation(1–5). C1P (Fig. 1a) produced by ceramide kinase is an activator of group IVA cytosolic phospholipase A(2)α (cPLA(2)α), the...

Descripción completa

Detalles Bibliográficos
Autores principales: Simanshu, Dhirendra K., Kamlekar, Ravi Kanth, Wijesinghe, Dayanjan S., Zou, Xianqiong, Zhai, Xiuhong, Mishra, Shrawan K., Molotkovsky, Julian G., Malinina, Lucy, Hinchcliffe, Edward H., Chalfant, Charles E., Brown, Rhoderick E., Patel, Dinshaw J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951269/
https://www.ncbi.nlm.nih.gov/pubmed/23863933
http://dx.doi.org/10.1038/nature12332