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Chimeric Proton-Pumping Rhodopsins Containing the Cytoplasmic Loop of Bovine Rhodopsin

G-protein-coupled receptors (GPCRs) transmit stimuli to intracellular signaling systems. Rhodopsin (Rh), which is a prototypical GPCR, possesses an 11-cis retinal. Photoisomerization of 11-cis to all-trans leads to structural changes in the protein of cytoplasmic loops, activating G-protein. Microbi...

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Detalles Bibliográficos
Autores principales: Sasaki, Kengo, Yamashita, Takahiro, Yoshida, Kazuho, Inoue, Keiichi, Shichida, Yoshinori, Kandori, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951393/
https://www.ncbi.nlm.nih.gov/pubmed/24621599
http://dx.doi.org/10.1371/journal.pone.0091323