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Chimeric Proton-Pumping Rhodopsins Containing the Cytoplasmic Loop of Bovine Rhodopsin
G-protein-coupled receptors (GPCRs) transmit stimuli to intracellular signaling systems. Rhodopsin (Rh), which is a prototypical GPCR, possesses an 11-cis retinal. Photoisomerization of 11-cis to all-trans leads to structural changes in the protein of cytoplasmic loops, activating G-protein. Microbi...
Autores principales: | Sasaki, Kengo, Yamashita, Takahiro, Yoshida, Kazuho, Inoue, Keiichi, Shichida, Yoshinori, Kandori, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951393/ https://www.ncbi.nlm.nih.gov/pubmed/24621599 http://dx.doi.org/10.1371/journal.pone.0091323 |
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