ABCB1 1199G>A Genetic Polymorphism (Rs2229109) Influences the Intracellular Accumulation of Tacrolimus in HEK293 and K562 Recombinant Cell Lines

OBJECTIVE: ATP-binding cassette, subfamily B, member 1 (ABCB1) transporter, or P-glycoprotein, is an efflux protein implicated in the absorption and the distribution of various compounds, including tacrolimus and cyclosporine A. In vivo studies suggest an association between the ABCB1 1199G>A sin...

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Detalles Bibliográficos
Autores principales: Dessilly, Géraldine, Elens, Laure, Panin, Nadtha, Capron, Arnaud, Decottignies, Anabelle, Demoulin, Jean-Baptiste, Haufroid, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951418/
https://www.ncbi.nlm.nih.gov/pubmed/24621983
http://dx.doi.org/10.1371/journal.pone.0091555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951418/
https://www.ncbi.nlm.nih.gov/pubmed/24621983
http://dx.doi.org/10.1371/journal.pone.0091555

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