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Assessing Specific Oligonucleotides and Small Molecule Antibiotics for the Ability to Inhibit the CRD-BP-CD44 RNA Interaction

Studies on Coding Region Determinant-Binding Protein (CRD-BP) and its orthologs have confirmed their functional role in mRNA stability and localization. CRD-BP is present in extremely low levels in normal adult tissues, but it is over-expressed in many types of aggressive human cancers and in neonat...

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Detalles Bibliográficos
Autores principales: King, Dustin T., Barnes, Mark, Thomsen, Dana, Lee, Chow H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951440/
https://www.ncbi.nlm.nih.gov/pubmed/24622399
http://dx.doi.org/10.1371/journal.pone.0091585