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Targeting SUR1/Abcc8-Type Neuroendocrine K(ATP) Channels in Pancreatic Islet Cells
ATP-sensitive K(+) (K(ATP)) channels play a regulatory role in hormone-secreting pancreatic islet α-, β- and δ-cells. Targeted channel deletion would assist analysis and dissection of the intraislet regulatory network. Toward this end Abcc8/Sur1 flox mice were generated and tested by crossing with g...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951447/ https://www.ncbi.nlm.nih.gov/pubmed/24621811 http://dx.doi.org/10.1371/journal.pone.0091525 |